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—— SIMPOR PHARMA
—— Nasir
—— IATEC, Argentyna
—— Mohammed Saad
The most fundamental basis is the required cleanliness level (such as ISO 5 to ISO 9). Higher classes demand more advanced air filtration systems (HEPA/ULPA filters), higher air change rates, and stricter sealing, which directly push up costs.
The total square footage, ceiling height, and complexity of the layout (e.g., number of rooms, pass-throughs, airlocks) significantly impact costs. Customized layouts with irregular shapes or multiple zones require more engineering and materials.
The heating, ventilation, and air conditioning (HVAC) system is a major cost component. Factors include the type of air filters, air handling units (AHUs), ductwork, and temperature/humidity control requirements. Precise climate control for sensitive industries (like pharmaceuticals) adds extra expenses.
The choice of wall panels (e.g., stainless steel, aluminum composite, PVC), flooring (epoxy, vinyl), and ceiling materials affects both upfront and long-term maintenance costs. Durable, easy-to-clean materials suitable for sterile environments are more expensive.

